Friday, June 25, 2021

CEFXER CV : THE TOUGH COMBINATION FOR TOUGHER SITUATIONS



Cefuroxime and Clavulanic Acid

A combination of cefuroxime and ß -lactamase inhibitor (Clavulanic acid) for the treatment of various bacterial infections.

CEFUROXIME : Bactericidal action due to inhibition of cell-wall synthesis.

Clavulanic Acid : Enzyme inhibitor that enhances the antibacterial activity

Why is this medication prescribed ?

Cefuroxime is used to treat certain infections caused by bacteria, such as bronchitis (infection of the airway tubes leading to the lungs); gonorrhea (a sexually transmitted disease); Lyme disease (an infection that may develop after a person is bitten by a tick); and infections of the skin, ears, sinuses, throat, tonsils,, and urinary tract. Cefuroxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as cefuroxime will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Cefuroxime comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours for 5-10 days, depending on the condition being treated. To treat gonorrhea, cefuroxime is taken as a single dose, and to treat Lyme disease, cefuroxime is taken every 12 hours for 20 days. Take the suspension with food; the tablet may be taken with or without food . Take cefuroxime at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefuroxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Different cefuroxime products are absorbed by the body in different ways and cannot be substituted for one another. If you need to switch from one cefuroxime product to another, your doctor may need to adjust your dose.

Shake the suspension well before each use to mix the medication evenly.

The tablets should be swallowed whole. Because the crushed tablet has a strong bitter taste, the tablet should not be crushed. Children who cannot swallow the tablet whole should take the liquid instead.

You should begin to feel better during the first few days of treatment with cefuroxime. If your symptoms do not improve or get worse, call your doctor.

Take cefuroxime until you finish the prescription, even if you feel better. If you stop taking cefuroxime too soon or skip doses, your infection may not be completely treated, and the bacteria may become resistant to antibiotics.

Other uses for this medicine

Cefuroxime is also sometimes used to treat pneumonia. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cefuroxime,

tell your doctor and pharmacist if you are allergic to cefuroxime.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

if you are taking antacids that contain magnesium or aluminum, take them at least 1 hour before or 2 hours after cefuroxime.

tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney or liver disease.

you should know that cefuroxime decreases the effectiveness of some oral contraceptives ('birth control pills). You will need to use another form of birth control while taking this medication. Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefuroxime, call your doctor.

if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that cefuroxime suspension is sweetened with aspartame that forms phenylalanine.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefuroxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

·         nausea

·         vomiting

·         diarrhea

Cefuroxime may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 10 days.

Symptoms of overdose may include:

·         Seizures

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cefuroxime.

Do not let anyone else take your medication. Your prescription is probably not refillable.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

CEFXER 500

CEFXER CV


 


For more information contact :

www.alisierdrugs.com

www.alisierdrugs.in

info@alisierdrugs.com

Mobile : 7206609999

Whatsapp : 9812039777

Thursday, June 3, 2021

THEOFRESH PLUS (NAC) – A POWERFUL MUCOLYTIC

 

THEOFRESH PLUS (NAC) – A POWERFUL MUCOLYTIC




N-acetyl cysteine (NAC) is used by the body to build antioxidants. Antioxidants are vitamins, minerals, and other nutrients that protect and repair cells from damage.

You can get NAC as a supplement or a prescription drug.

Why do people take NAC?

As a prescription drug, doctors use NAC to treat acetaminophen overdose. It may also help break up mucus in people with some lung diseases, like chronic bronchitis.

As a supplement, some people use NAC to try to protect the liver. There's evidence it can help prevent kidney or neurologic damage caused by some drugs.

N-acetylcysteine (NAC) is the supplement form of the amino acid cysteine. Proponents claim that taking N-acetylcysteine supplements can protect against a plethora of health concerns, including respiratory diseases, liver disease, psychiatric disorders, diabetes, certain cancers, and chemical dependency.


Health Benefits

In complementary and alternative medicine (CAM), N-acetylcysteine is believed to help a wide range of medical conditions. Because N-acetylcysteine can increase the production of glutathione, some practitioners have posited that it not only prevents conditions like cancer and heart disease by maintaining the integrity of cells, but also support the treatment of certain diseases.

Proponents contend that N-acetylcysteine has the potential to prevent or treat an almost encyclopedic range of health problems, including:

  • Allergic rhinitis (hay fever)
  • Alzheimer's disease
  • Bipolar disorder
  • Bronchitis
  • Carbon dioxide poisoning
  • Chronic kidney disease
  • Chronic obstructive pulmonary disorder (COPD)
  • Cirrhosis
  • Cocaine dependence
  • Colorectal cancer
  • Conjunctivitis
  • Cystic fibrosis
  • Heart disease
  • Hepatitis
  • Hypercholesterolemia (high cholesterol)
  • HIV
  • Infertility
  • Lou Gehrig's disease
  • Lung cancer
  • Lupus
  • Polycystic ovary syndrome (PCOS)
  • Post-traumatic distress syndrome (PTSD)
  • Preterm labor or miscarriage
  • Schizophrenia
  • Unstable angina
  • Upper respiratory infections

The expansive nature of these claims borders on far-fetched. Even those claims for which there is at least some related clinical research typically fall short, either because the studies are small or the evidence doesn't support the often over-reaching conclusions.

With that being said, there have been some positive findings that warrant serious scientific consideration. Here is a look at some of the research investigating the benefits of N-acetylcysteine supplements.

Mechanism of action

A number of possible mechanisms for the mucolytic activity of acetylcysteine have been proposed. Acetylcysteine's sulfhydryl groups may hydrolize disulfide bonds within mucin, breaking down the oligomers, and making the mucin less viscous.11,16 Acetylcysteine has also been shown to reduce mucin secretion in rat models.11 It is an antioxidant in its own right but is also deacetylated to cysteine, which participates in the synthesis of the antioxidant glutathione.11 The antioxidant activity may also alter intracellular redox reactions, decreasing phosphorylation of EGFR and MAPK, which decrease transcription of the gene MUC5AC which produces mucin.11

In the case of acetaminophen overdoses, a portion of the drug is metabolized by CYP2E1 to form the potentially toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI).16 The amount of NAPQI produced in an overdose saturates and depletes glutathione stores.16 The free NAPQI promiscuously binds to proteins in hepatocytes, leading to cellular necrosis.16 Acetylcysteine can directly conjugate NAPQI or provide cysteine for glutathione production and NAPQI conjugation.16

 


A Word From Alisier

Only minute amounts of N-acetylcysteine are found in food. Still, cysteine deficiency is not very common, although vegetarians and vegans with a low intake of cysteine-rich plant foods may be at risk.

Those working to make sure they have adequate levels of NAC can consider supplementation, but should also be mindful about consuming these foods, which are excellent food sources of the amino acid: poultry, eggs, dairy, red peppers, garlic, onions, broccoli, Brussels sprouts, oats, and wheat germ.

Our THEOFRESH PLUS known for its ability to replenish levels of the antioxidant glutathione, it also regulates the important brain neurotransmitter glutamate. Additionally, THEOFRESH PLUS helps the body’s detoxification system. These functions make NAC supplements a viable treatment option for multiple health problems.

 

For more information contact :

www.alisierdrugs.com

www.alisierdrugs.in

info@alisierdrugs.com

Mobile : 7206609999

Whatsapp : 9812039777

SIKRIGO

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