CEFXER CV : THE TOUGH COMBINATION FOR TOUGHER SITUATIONS

Cefuroxime and Clavulanic Acid

A combination of cefuroxime and ß -lactamase inhibitor (Clavulanic acid) for the treatment of various bacterial infections.

CEFUROXIME : Bactericidal action due to inhibition of cell-wall synthesis.

Clavulanic Acid : Enzyme inhibitor that enhances the antibacterial activity

Why is this medication prescribed ?

Cefuroxime is used to treat certain infections caused by bacteria, such as bronchitis (infection of the airway tubes leading to the lungs); gonorrhea (a sexually transmitted disease); Lyme disease (an infection that may develop after a person is bitten by a tick); and infections of the skin, ears, sinuses, throat, tonsils,, and urinary tract. Cefuroxime is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as cefuroxime will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Cefuroxime comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken every 12 hours for 5-10 days, depending on the condition being treated. To treat gonorrhea, cefuroxime is taken as a single dose, and to treat Lyme disease, cefuroxime is taken every 12 hours for 20 days. Take the suspension with food; the tablet may be taken with or without food . Take cefuroxime at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefuroxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Different cefuroxime products are absorbed by the body in different ways and cannot be substituted for one another. If you need to switch from one cefuroxime product to another, your doctor may need to adjust your dose.

Shake the suspension well before each use to mix the medication evenly.

The tablets should be swallowed whole. Because the crushed tablet has a strong bitter taste, the tablet should not be crushed. Children who cannot swallow the tablet whole should take the liquid instead.

You should begin to feel better during the first few days of treatment with cefuroxime. If your symptoms do not improve or get worse, call your doctor.

Take cefuroxime until you finish the prescription, even if you feel better. If you stop taking cefuroxime too soon or skip doses, your infection may not be completely treated, and the bacteria may become resistant to antibiotics.

Other uses for this medicine

Cefuroxime is also sometimes used to treat pneumonia. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cefuroxime,

tell your doctor and pharmacist if you are allergic to cefuroxime.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

if you are taking antacids that contain magnesium or aluminum, take them at least 1 hour before or 2 hours after cefuroxime.

tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney or liver disease.

you should know that cefuroxime decreases the effectiveness of some oral contraceptives ('birth control pills). You will need to use another form of birth control while taking this medication. Talk to your doctor about other ways to prevent pregnancy while you are taking this medication.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefuroxime, call your doctor.

if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that cefuroxime suspension is sweetened with aspartame that forms phenylalanine.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefuroxime may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

·         nausea

·         vomiting

·         diarrhea

Cefuroxime may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from excess heat and moisture (not in the bathroom). Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 10 days.

Symptoms of overdose may include:

·         Seizures

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cefuroxime.

Do not let anyone else take your medication. Your prescription is probably not refillable.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

CEFXER 500

CEFXER CV

 

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THEOFRESH PLUS (NAC) – A POWERFUL MUCOLYTIC

 

THEOFRESH PLUS (NAC) – A POWERFUL MUCOLYTIC

N-acetyl cysteine (NAC) is used by the body to build antioxidants. Antioxidants are vitamins, minerals, and other nutrients that protect and repair cells from damage.

You can get NAC as a supplement or a prescription drug.

Why do people take NAC?

As a prescription drug, doctors use NAC to treat acetaminophen overdose. It may also help break up mucus in people with some lung diseases, like chronic bronchitis.

As a supplement, some people use NAC to try to protect the liver. There's evidence it can help prevent kidney or neurologic damage caused by some drugs.

N-acetylcysteine (NAC) is the supplement form of the amino acid cysteine. Proponents claim that taking N-acetylcysteine supplements can protect against a plethora of health concerns, including respiratory diseases, liver disease, psychiatric disorders, diabetes, certain cancers, and chemical dependency.

Health Benefits

In complementary and alternative medicine (CAM), N-acetylcysteine is believed to help a wide range of medical conditions. Because N-acetylcysteine can increase the production of glutathione, some practitioners have posited that it not only prevents conditions like cancer and heart disease by maintaining the integrity of cells, but also support the treatment of certain diseases.

Proponents contend that N-acetylcysteine has the potential to prevent or treat an almost encyclopedic range of health problems, including:

• Allergic rhinitis (hay fever)
• Alzheimer's disease
• Bipolar disorder
• Bronchitis
• Carbon dioxide poisoning
• Chronic kidney disease
• Chronic obstructive pulmonary disorder (COPD)
• Cirrhosis
• Cocaine dependence
• Colorectal cancer
• Conjunctivitis
• Cystic fibrosis
• Heart disease
• Hepatitis
• Hypercholesterolemia (high cholesterol)
• HIV
• Infertility
• Lou Gehrig's disease
• Lung cancer
• Lupus
• Polycystic ovary syndrome (PCOS)
• Post-traumatic distress syndrome (PTSD)
• Preterm labor or miscarriage
• Schizophrenia
• Unstable angina
• Upper respiratory infections

The expansive nature of these claims borders on far-fetched. Even those claims for which there is at least some related clinical research typically fall short, either because the studies are small or the evidence doesn't support the often over-reaching conclusions.

With that being said, there have been some positive findings that warrant serious scientific consideration. Here is a look at some of the research investigating the benefits of N-acetylcysteine supplements.

Mechanism of action

A number of possible mechanisms for the mucolytic activity of acetylcysteine have been proposed. Acetylcysteine's sulfhydryl groups may hydrolize disulfide bonds within mucin, breaking down the oligomers, and making the mucin less viscous.^11,16 Acetylcysteine has also been shown to reduce mucin secretion in rat models.¹¹ It is an antioxidant in its own right but is also deacetylated to cysteine, which participates in the synthesis of the antioxidant glutathione.¹¹ The antioxidant activity may also alter intracellular redox reactions, decreasing phosphorylation of EGFR and MAPK, which decrease transcription of the gene MUC5AC which produces mucin.¹¹

In the case of acetaminophen overdoses, a portion of the drug is metabolized by CYP2E1 to form the potentially toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI).¹⁶ The amount of NAPQI produced in an overdose saturates and depletes glutathione stores.¹⁶ The free NAPQI promiscuously binds to proteins in hepatocytes, leading to cellular necrosis.¹⁶ Acetylcysteine can directly conjugate NAPQI or provide cysteine for glutathione production and NAPQI conjugation.¹⁶

 

A Word From Alisier

Only minute amounts of N-acetylcysteine are found in food. Still, cysteine deficiency is not very common, although vegetarians and vegans with a low intake of cysteine-rich plant foods may be at risk.

Those working to make sure they have adequate levels of NAC can consider supplementation, but should also be mindful about consuming these foods, which are excellent food sources of the amino acid: poultry, eggs, dairy, red peppers, garlic, onions, broccoli, Brussels sprouts, oats, and wheat germ.

Our THEOFRESH PLUS known for its ability to replenish levels of the antioxidant glutathione, it also regulates the important brain neurotransmitter glutamate. Additionally, THEOFRESH PLUS helps the body’s detoxification system. These functions make NAC supplements a viable treatment option for multiple health problems.

 

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PROTECT PREGNANCY WITH PROGESTERONE (KEEPGEST)

PROTECT PREGNANCY WITH PROGESTERONE (KEEPGEST)

Progesterone is a hormone that occurs naturally in the body. It can also be made in a laboratory.

"Progestin" is a general term for a substance that causes some or all of the biologic effects of progesterone. The term "progestin" is sometimes used to refer to the progesterone made in the laboratory that is in oral contraceptives and hormone replacement therapy. However, all progesterone and progestin products are made in the laboratory. The term "natural progesterone" is really a misnomer. "Natural progesterones," including the prescription products Crinone and Prometrium, are made from a chemical called diosgenin that is isolated from wild yam or soy. In the laboratory, diosgenin is converted to progesterone. The human body is not able to make progesterone from diosgenin, so eating wild yam or soy will not boost your progesterone levels.

What Does Progesterone Do?

Progesterone prepares the endometrium for the potential of pregnancy after ovulation. It triggers the lining to thicken to accept a fertilized egg. It also prohibits the muscle contractions in the uterus that would cause the body to reject an egg. While the body is producing high levels of progesterone, the body will not ovulate.

If the woman does not become pregnant, the corpus luteum breaks down, lowering the progesterone levels in the body. This change sparks menstruation. If the body does conceive, progesterone continues to stimulate the body to provide the blood vessels in the endometrium that will feed the growing fetus. The hormone also prepares the limit of the uterus further so it can accept the fertilized egg.

Once the placenta develops, it also begins to secrete progesterone, supporting the corpus luteum. This causes the levels to remain elevated throughout the pregnancy, so the body does not produce more eggs. It also helps prepare the breasts for milk production.

What happens if I have too much progesterone?

There are no known serious medical consequences of having too much progesterone. Levels of progesterone do increase naturally in pregnancy as mentioned above.

High levels of progesterone are associated with the condition congenital adrenal hyperplasia' data-content='1315' >congenital adrenal hyperplasia. However, the high progesterone levels are a consequence of and not a cause of this condition. Also, high levels of progesterone are associated with an increased risk for developing breast cancer.

Progesterone, either alone or in combination with oestrogen, is taken by women as an oral contraceptive ('the pill'). 'The pill' works by preventing ovulation, making it nearly 100% effective in preventing pregnancy.

Progesterone is used in hormone replacement therapy to relieve symptoms of the menopause in women. There are many recognised pros and cons to hormone replacement therapy – see the article on menopause for more information.

What happens if I have too little progesterone?

If progesterone is absent or levels are too low, irregular and heavy menstrual bleeding can occur. A drop in progesterone during pregnancy can result in a miscarriage and early labour. Mothers at risk of giving birth too soon can be given a synthetic form of progesterone to delay the onset of labour. 

Lack of progesterone in the bloodstream can mean the ovary has failed to release an egg at ovulation, as can occur in women with polycystic ovary syndrome.

Progesterone (Natural Micronized) 200mg

KEEPGEST 200 (Natural Micronized Progesterone) is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.

Progesterone 300mg Sustained Released

KEEPGEST SR 300MG contains Progesterone which belongs to the group of medicine called progestins. It is used to treat abnormal uterine bleeding characterized by heavy periods, irregular periods or bleeding between periods, after sex, or during menopause. It can also be used to treat benign mastopathies which are painful disorders of the breast and symptoms of pre-menopause (such as hot flushes, anxiety, depression or vaginal dryness).

Progesterone 500mg Injection

KEPGEST 500mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

 

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An Essential Care for Joyful Pregnancy (ISOTROPIC)

 

What is Isoxsuprine?

Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

These actions may help treat the symptoms of conditions such as cerebral vascular insufficiency (poor blood flow to the brain), arteriosclerosis (hardening of the arteries).

How should this medicine be used?

Isoxsuprine comes as a tablet to take by mouth. It is usually taken three or four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isoxsuprine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Other uses for this medicine

Isoxsuprine is also used occasionally to treat menstrual pain or prevent premature labor. Talk to your doctor about the possible risks of using this drug for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What is the most important information I should know about Isoxsuprine (Isotropic)?

Isoxsuprine should not be used immediately postpartum (after delivering a baby), or if you have a bleeding disorder. Talk to your doctor about any other medical conditions that you have.

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether isoxsuprine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

 

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Improve Immunity with Alisveda Ayush Kwath Powder (Kadha)

 

Ayush Kwath

What is Ayush Kwath Kadha?

Known as one of the best medicines to promote immunity in Ayurveda, Ayush Kwath Kadha is a healthy drink made of essential spices and immunity-boosting herbs. In ancient days, this drink used to be made by boiling the herbs in water. All the benefits of the herbs were extracted in the water and hence, drinking it was the best way to prevent diseases. Ayush Kwath Powder makes the process much easier. Formulated with Tulsi, Dalchini, Sunthi, and Kali Mirch, it comes in a powder format. All you need to do is boil this powder in water and consume it. This kadha for fever and cold is especially beneficial during winter and monsoon seasons when allergies and infections are prevalent. Once ready, you can sip on this drink all through the day or leave it in the fridge and use it again after preheating. It is helpful in treating allergies, throat infections, cough, and cold. It is recommended for people who fall sick often. The herbal ingredients in this kadha help stimulate digestion, boost immunity, and detox the body. Regular use helps you combat all viral and bacterial infections and leaves you healthy with a strong immune system.

 

Description:

Formulated with Ayurvedic immunity-boosting herbs such as Tulsi, Dalchini, Sunthi, and Kali Mirch, Alisveda Ayush Kwath Kadha Powder can be had for its myriad health benefits. This Ayurvedic immunity booster keeps infections and diseases at outskirts. Regular consumption of this Ayurvedic kadha for immunity strengthens the immune system in children and the elderly. Ayurvedic experts believe that the antiviral and antibacterial properties in this kadha for immunity boosting will effectively keep you healthy and infection-free always. One of the best among the Ayurvedic medicines for immunity improvement, this Ayush kadha powder creates an invisible shield against contagious illnesses in a natural and herbal way.

 

Alisveda Ayush Kwath Powder Uses and Benefits:

·         Ayurvedic medicine for improving immunity: Helps improve the immune system internally and protects the body from symptoms of infections.

·         Provides Protection from Infections: This Ayurvedic medicine for immunity and strength contains Tulsi, Dalchini, Sunthi, and Kali Mirch that help relieve symptoms associated with infections. This works as a kadha for viral fever as well.

·         Ayurvedic Kadha for Cold and Cough: The antibacterial, antiviral and antifungal properties of Tulsi along with the anti inflammatory and antioxidant properties of Sunthi will help in easing cold and cough. Enriched with the power of these ayurvedic herbs for the immune system, this kadha also acts as an Ayurvedic immunity booster for kids.

·         Potent Antioxidant: This immunity booster kadha has antioxidant properties as well. An effective antioxidant, Dalchini helps fight infections and build immunity.

·         100% natural and safe: This Ayurvedic medicine to increase immunity is made with responsibly sourced pure Ayurvedic ingredients that are 100% natural; free from chemicals, preservatives, and flavors, no added sugar.

How to Use

You can have it once or twice daily. Take 1 teaspoon (3gm) Ayush Kwath powder and infuse it in 150ml of boiled water and consume it like tea or a hot drink. You can add gud (jaggery)/draksha (raisins) and/or lemon juice with it for sweetness.

Storage Information:

·         Store at room temperature and keep it protected from moisture and direct sunlight.

·         Secure the jar tightly after every use.

 

Key Features

Recommended by Ministry of Ayush, GOI

Enhances body’s defence against infections

Contains herbal ingredients

Known to boost immunity

Contains no preservatives, additives or diluents

Promotes overall health

 

Article from Website

SARS-CoV-2 infection associated respiratory disease- COVID-19 has evolved into a pandemic but, being a new form of virus, pathogenesis of disease causation is not fully understood and drugs and vaccines against this virus are still being tested so that no effective drugs or vaccines have been advised by regulatory authority. In this context, the Ministry of AYUSH, Government of India has recommended ‘Ayush Kwath’ to improve the immunity and combat the infection. Our objective of this literature review is to review the role of immunity in pathogenesis of COVID-19 and role of Ayush Kwath against the virus and regulation of immunity. Current review was conducted using a search of available literature on COVID-19 and immunity, Vyadhikshamatwa, Ayurveda and COVID-19, Rasayana, Coronavirus, SARS-CoV-2, immunomodulatory effects of medicinal plants; Tulsi/Holy Basil/Ocimum sanctum, Dalchini/Cinnamon/Cinnamomum zeylanicum, Sunthi/Ginger/Zingiber officinale and Marich/Black Pepper/Piper nigrum. Ayurveda, being an ancient science have both medicinal and cultural values and had stimulated our kitchen and influenced what we ate in different seasons and the remedies we used for common ailments. Herbs such as Tulsi, Marich, Sunthi, Dalchini are the most commonly used and easily available drugs in home. Thus, Ayush Kwath due to its immune-modulatory, antiviral, anti-oxidant, anti-inflammatory, anti-platelet, anti-atherosclerotic, hepato-protective, reno-protective properties; seems to be effective in immuno-regulation for controlling viral infections like COVID-19. Further pre-clinical and clinical trials need to be done for the evaluation of safety and efficacy of this polyherbal formulation.

Reference : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430223/

 

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